The Computational Biology Center (cBio) at Memorial Sloan-Kettering Cancer Center (MSKCC) pursues computational and systems biology research and bioinformatics resource development in the following areas:

  • cancer genomics and proteomics
  • molecular pathways and networks
  • gene regulation
  • tumor-stromal cell interactions
  • cell-to-cell communication
  • self/non-self discrimination in immunology & cancer biology
  • sequence-structure analysis
  • diagnostic and prognostic markers
  • design of combinatorial cancer therapy
  • social interaction in microbes
  • human microbiome


The mission of cBio is to move the theoretical methods and genome-scale data resources of computational biology into everyday laboratory practice and use.

This is reflected in the organization of cBio into research and service components, with the intention of generalizing new computational methods created through the process of scientific inquiry, and supporting them as open-source and shared community resources.

Research: cBio currently has four research groups led by Dana Pe'er, John Chodera, Christina Leslie, and Joao Xavier.



We are located in the Upper East Side of Manhattan in New York City.

Zuckerman Research Center
417 East 68th Street – 6th and 11th Floors
New York, NY 10065

Ask your driver to drop you off at the corner of 68th St. and 1st Avenue. Walk east towards York Avenue.

To reach us from downtown, take the #6 train uptown to 68 Street-Hunter College. Walk three and one-half blocks east on 68th Street to the Center (approximately 5 to 10 minutes).

Subway schedules and maps are available from the New York City MTA.

Our offices are indicated by the green arrow in the map below.