About cPath

cPath is an open source pathway database and software suite designed for systems biology research.

Main features include:

• Import pipeline capable of aggregrating pathway and interaction data sets from multiple sources, including: MINT, IntAct, HPRD, DIP, BioCyc, KEGG, PUMA2 and Reactome.
• Import/Export support for the Proteomics Standards Initiative Molecular Interaction (PSI-MI) and the Biological Pathways Exchange (BioPAX) XML formats.
• Data visualization and analysis via Cytoscape .
• Simple HTTP URL based XML web service.
• Complete software is freely available for local install. Easy to install and administer.
• Partly funded by the U.S. National Cancer Institute, via the Cancer Biomedical Informatics Grid (caBIG) , and aims to meet "silver-level" requirements for software interoperability and data exchange.

cPath is currently being developed by the Computational Biology Center at Memorial Sloan-Kettering Cancer Center .

For additional details regarding cPath, please refer to our recent paper:

• Ethan G Cerami, Gary D Bader, Benjamin E Gross, and Chris Sander, cPath: open source software for collecting, storing, and querying biological pathways BMC Bioinformatics 2006, 7:497 [doi:10.1186/1471-2105-7-497 ] [Pub Med ] [Full Text ]

About the cPath Demo Site

A demo version of cPath is currently available at: http://cbio.mskcc.org/cpath . This site is currently running in PSI-MI mode, and contains PSI-MI Level 1 data from: IntAct and MINT .

cPath Developer Mailing List

Get involved. Join the cpath-dev mailing list.