Cancer Genomics

Introduction

Integrative Analysis of Cancer Genomics Data

photo

A major focus at the Computational Biology Center at Memorial Sloan- Kettering Cancer Center is the integrative analysis of cancer genomics data sets.

Methods developed at cBio span the analysis of mutations, identification of recurrent DNA copy-number alterations, and the identification of altered signaling pathways.

This website presents the results of detailed analysis of four cancer types: Prostate cancer, Sarcoma, Glioblastoma, and Serous Ovarian Cancer. The site also provides access to analysis tools in the areas of signaling pathways, mutations, and copy number alterations.

Cancer Genomics Sidebar

Data Portal

Explore cancer genomics data via the cBio Cancer Genomics Portal.

News

The CGDS R-package has been released.

NetBox version 1 has been released.

The Cancer Genome Atlas has announced the selection of six Genome Data Analysis Centers.

Publications

Mutual exclusivity analysis identifies oncogenic network modules. Genome Res. 2011 Sep 9. [Abstract] [PDF]

Integrated genomic analyses of ovarian carcinoma. Nature. 2011 Jun 29. [Abstract] [Full Text] [PDF]

Pathway Commons, a web resource for biological pathway data. Nucleic Acids Res.. 2011 Jan (Database issue). [Abstract] [Full Text] [PDF]

Gene Ranker

Explore cancer genes with Gene Ranker.