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Publications
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs. (2009)
Nat Biotechnol. 2009 Jun;27(6):549-55.
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Characterization of small RNAs in aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB. (2009)
Neuron. 2009 Sep 24;63(6):803-17.
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The microRNA.org resource: targets and expression. (2008)
Nucleic Acids Res. 2008 Jan;36(Database issue):D149-53.
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Computational analysis of mouse piRNA sequence and biogenesis. (2007)
PLoS Comput Biol. 2007 Nov;3(11):e222.
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Structure-Templated Predictions of Novel Protein Interactions from Sequence Information. (2007)
PLoS Comput Biol. 2007 Sep 21;3(9):e182.
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The Biomolecular Interaction Network Database and related tools 2005 update. (2005)
Nucleic Acids Res. 2005 Jan 1;33(Database issue):D418-24.
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Analysis of domain correlations in yeast protein complexes. (2004)
Bioinformatics. 2004 Aug 4;20 Suppl 1:I55-I62.
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BIND: the Biomolecular Interaction Network Database. (2003)
Nucleic Acids Res. 2003 Jan 1;31(1):248-50.
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SeqHound: biological sequence and structure database as a platform for bioinformatics research. (2002)
BMC Bioinformatics. 2002 Oct 25;3:32. Epub 2002 Oct 25.
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Kangaroo--a pattern-matching program for biological sequences. (2002)
BMC Bioinformatics. 2002 Jul 31;3:20.
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Mutation profiling of mismatch repair-deficient colorectal cncers using an in silico genome scan to identify coding microsatellites. (2002)
Cancer Res. 2002 Mar 1;62(5):1284-8.
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Agile methods in biomedical software development: a multi-site experience report. (2006)
BMC Bioinformatics. 2006 May 30;7(1):273.
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cPath: open source software for collecting, storing, and querying biological pathways. (2006)
BMC Bioinformatics. 2006;7:497.
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Web Services Essentials: Distributed Applications with XML-RPC, SOAP, UDDI & WSDL (2002)
O'Reilly: 304 page paperback
ISBN: 0-596-00224-6
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PATIKAweb: a Web interface for analyzing biological pathways through advanced querying and visualization. (2006)
Bioinformatics. 2006 Feb 1;22(3):374-5.
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An ontology for collaborative construction and analysis of cellular pathways (2004)
Bioinformatics. 2004 Feb 12;20(3):349-56
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PATIKA: an integrated visual environment for collaborative construction and analysis of cellular pathways. (2002)
Bioinformatics. 2002 Jul;18(7):996-1003.
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Threading with chemostructural restrictions method for predicting fold and functionally significant residues: application to dipeptidylpeptidase IV (DPP-IV) (2002)
Proteins. 2002 May 1;47(2):180-93
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Determining the roles of different chain fragments in recognition of immunoglobulin fold (1999)
Protein Eng. 2002 Jan;15(1):13-9
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Averaging interaction energies over homologs improves protein fold recognition in gapless threading (1999)
Proteins. 1999 May 15;35(3):353-9
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Optimization of protein structure on lattices using a self-consistent field approach (1998)
J Comput Biol. 1998 Fall;5(3):531-8
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What is the probability of a chance prediction of a protein structure with an rmsd of 6 A (1998)
Fold Des. 1998;3(2):141-7
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Accurate mean-force pairwise-residue potentials for discrimination of protein folds (1997)
Pac Symp Biocomput. 1997;:373-84.
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Residue-residue mean-force potentials for protein structure recognition (1997)
Protein Eng. 1997 Aug;10(8):865-76
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Recognition of protein structure on coarse lattices with residue-residue energy functions (1997)
Protein Eng. 1997 Oct;10(10):1123-30
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A mammalian microRNA expression atlas based on small RNA library sequencing. (2007)
Cell. 2007 Jun 29;129(7):1401-14.
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Determinants of protein function revealed by combinatorial entropy optimization. (2007)
Genome Biol. 2007;8(11):R232.
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A novel class of small RNAs bind to MILI protein in mouse testes. (2006)
Nature. 2006 Jun 4;
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Signal processing in the TGF-beta superfamily ligand-receptor network (2006)
PloS Computational Biology, Jan; 2 (1) :e3
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Pathguide: a pathway resource list. (2006)
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D504-6.
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Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development. (2005)
Cell. 2005 Jul 1;121(7):1097-108.
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Identification of microRNAs of the herpesvirus family. (2005)
Nat Methods. 2005 Apr;2(4):269-76.
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MicroRNA profiling of the murine hematopoietic system. (2005)
Genome Biol. 2005;6(8):R71.
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Pathway information for systems biology. (2005)
FEBS Lett. 2005 Mar 21;579(8):1815-20.
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The developmental miRNA profiles of zebrafish as determined by small RNA cloning. (2005)
Genes Dev. 2005 Jun 1;19(11):1288-93.
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miR-122, a Mammalian Liver-Specific microRNA, is Processed from hcr mRNA and May Downregulate the High Affinity Cationic Amino Acid Transporter CAT-1 (2004)
RNA Biology 1:2, 106-113; July/August
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Global mapping of the yeast genetic interaction network (2004)
Science. 2004 Feb 6;303(5659):808-13.
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Identification of virus-encoded microRNAs (2004)
Science. 2004 Apr 30;304(5671):734-6.
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Detection of activity centers in cellular pathways using transcriptional profiling (2004)
J Biopharm Stat. 2004 Aug;14(3):701-21.
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Evaluation of annotation strategies using an entire genome sequence (2003)
Bioinformatics. 2003 Apr 12;19(6):717-26
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Locating domains in protein 3D structures (2001)
In: International Tables for Crystallography, Volume F. Crystallography of Biological Macromolecules
Dordrecht: Kluwer Academic Publishers, The Netherlands
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A four-helix bundle modelling scaffold: the ROP protein (2001)
Protein Engineering 3, 298-299
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The GeneQuiz web server: protein functional analysis on the web (2000)
Trends Biochem Sci 25, 33-35
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CAST: an iterative algorithm for the complexity analysis of sequence tracts Ouzounis (2000)
Bioinformatics 16, 915-922
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Automated genome sequence analysis and annotation on the web (1999)
Bioinformatics 15, 391-412
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Protein folds and families: sequence and structure alignments (1999)
Nucleic Acids Res 27, 244-247
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EUCLID: automatic classification of proteins in functional classes by their database annotations (1998)
Bioinformatics 14, 542-543
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MView: a web compatible database search or multiple alignment viewer (1998)
Bioinformatics 14, 380-381
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Removing near-neighbor redundancy from large protein sequence collections (1998)
Bioinformatics 14, 423-429
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Updated catalog of human-disease related proteins in the yeast genome (1998)
FEBS Letters 426, 7-16
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The HSSP database of protein structure-sequence alignments and family profiles (1998)
Nucleic Acids Research 26, 313-315
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Predicting Protein Structure Using Hidden Markov Models (1997)
Proteins, Suppl. 1, 134-139
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Dali/FSSP classification of three-dimensional protein folds (1997)
Nucleic Acids Research 25, 231-234
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Sequence analysis of the Methanococcus janaschii genome and the prediction of protein function (1997)
Comp. Appl. Biosc. 13,481-483
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Classification of protein families and detection of the determinant residues with a self-organising neural network (1997)
Biological Cybernetics 76, 441-450
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Characterization of new proteins found by analysis of short open reading frames from the full yeast genome (1997)
Yeast, 13, 1363-1374
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An evolutionary treasure: Unification of a broad set of amidohydrolases related to urease (1997)
Proteins 28, 72-82
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Protein fold recognition by prediction-based threading. (1997)
J. Mol. Biol. 270, 471-480
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The HSSP database of protein structure-sequence alignments (1997)
Nucleic Acids Res 25, 226-230
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DNA sequencing and analysis of 130 kilobases from yeast chromosome XV (1997)
Yeast 13, 655-672
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Bioinformatics: from genome data to biological knowledge (1997)
Current Opinion in Biotechnology 8,675-683
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Novelties from the complete genome of Mycoplasma genitalium (1996)
Mol. Microbiol. 20, 897-899
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Bioinformatics and the discovery of gene function (1996)
Trends in Genetics 12, 244-245
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GeneQuiz II: automatic function assignment for genome sequence analysis (1996)
In: Proceedings of the First Annual Pacific Symposium on Biocomputing
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Sequencing and analysis of a 35.4 kb region on the left arm of chromosome IV from Saccharomyces cerevisiae reveal 23 open reading frames (1996)
Yeast 12, 1085-1090
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Macromolecular structure information and databases. The EU BRIDGE Database Project Consortium (1996)
Trends Biochem Sci 21: 251-256
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The FSSP database: fold classification based on structure-structure alignment of proteins (1996)
Nucl. Acids Res. 24, 206-210
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The PDBFinder database: a summary of PDB,DSSP and HSSP information with added value (1996)
Cabios 12, 525-529
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Verification of Protein Structures: Side-Chain Planarity (1996)
J. App. Cryst. 29, 714-716
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Positioning hydrogen atoms by optimizing hydrogen-bond networks in protein structures (1996)
Proteins 26, 363-376
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Bridging the protein sequence-structure gap by structure predictions (1996)
Ann. Rev. of Biophys. and Biomol. Structure, 25, 113-136
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The HSSP database of protein structure-sequence alignments (1996)
Nucleic Acids Res. 24, 201-205
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The prediction of protein contacts from multiple sequence alignments (1996)
Protein Engineering 9, 941-948
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A comparison of structural and dynamic properties of different simulation methods applied to SH3 (1996)
Biophys J 70: 684-692
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Sequence-function correlation in G protein-coupled receptors (1996)
In: Membrane Protein Models
BIOS Scientific Publishers: Oxford
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GeneCrunch: Experiences on the SGI POWER CHALLENGE array with Bioinformatic applications (1996)
In: Proceedings Supercomputing 96
K.G. Sauer Verlag
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Exploring the mycoplasma capricolum genome: a minimal cell reveals its physiology (1995)
Molecular Microbiology 16, 955-967
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The cytidyltransferase superfamily: identification of nucleotide binding site and fold prediction (1995)
Proteins 22, 259-266
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Challenging times for bioinformatics: Automated protein sequence analysis of the Haemophilus Influenzae genome (1995)
Nature 376, 647-648
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Sequence Space Analysis: Identification of Functionally and Structurally Important Residues in Protein Sequence Families (1995)
In: PROTEIN FOLDS: A Distance-Based Approach
CRC Press Inc.
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The use of position-specific rotamers in model building by homology (1995)
Proteins 23, 415-421
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Investigating the structural determinants of the ras p21-like triphosphate and Mg2+ binding site (1995)
J. Mol. Biol. 249, 654-664
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DNA polymerase belongs to an ancient nucleotidyltransferase superfamily (1995)
TIBS 20, 345-347
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Evolutionary link between glycogen phosphorylase and a DNA modifying enzyme (1995)
EMBO J.14, 1287-1293
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Fast protein structure database searches at 90% reliability (1995)
In: Proceedings of the Third International Conference on Intelligent Systems for Molecular Biology
AAAI Press, Menlo Park, California
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A drosophila hsp70 gene contains long, antiparallel, coupled open reading frames (LAC ORFs) conserved in homologous loci (1995)
J. Mol. Evol. 41, 414-420
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The functional composition of living machines (as a design principle for artificial organisms) (1995)
In: Advances in Artificial Life, Third European Conference on Artificial Life, Granada, Spain, June 1995, Proceedings
Springer Verlag, Heidelberg
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The ras superfamily (1995)
In: Guidebook to the Small GTPases
Sambrook and Tooze publication at Oxford University Press
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Nucleotide sequence and analysis of the centromeric region of yeast chromosome IX (1995)
Yeast 11, 61-78
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A sequence property approach to searching protein sequence databases (1995)
J. Mol. Biol. 251, 390-399
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A method to predict functional residues in proteins (1995)
Nature Struc Biol 2, 171-178
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Sequence-function correlation in G protein-coupled receptors (1995)
In: Membrane protein models
BIOS Sci. Pub. Ltd
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Comparative structure analysis (1995)
In: Making the Most of Your Model. Proceedings of the CCP4 Study Weekend held at Chester, January 1995
Daresbury Report Series
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Structural Design of Proteins (1994)
In: Concept of Protein Engineering and Design
Walter DeGruyter, Berlin
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Design of protein strutures: helical bundles and beyond (1994)
Trends in Biotechnology 12, 163-167
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From genome sequences to protein function (1994)
Curr. Opin. Struct. Biol. 4, 393-403
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Sequenzvergleiche in der Genomanalyse . In: Tagungsband, Bioinformatik:Computereinsatz in den Biowissenschaften (1994)
Jena, 59-60
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The chaperone function of DnaK requires the coupling of ATPase activity with substrate binding through residue E171 (1994)
EMBO J 13, 1687-1695
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A human cDNA coding for the Leydig insulin-like peptide Ley I-L (1994)
Human Genetics 94, 91-94
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Predicting local structural changes that result from point mutations (1994)
Protein Engineering 7, 1203-1208
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Amino acid analysis and protein database compositional search as a rapid and inexpensive method to identify proteins (1994)
Anal. Biochem. 222, 202-209
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Structural similarity of plant chitinase and lysozymes from animals and phage: an evolutionary connection (1994)
Febs Letters 340, 129-132
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Three sisters, different names: 3a,20b-hydroxysteroid dehydrogenase, dihydropteridine reductase, UDP-galactose 4-epimerase (1994)
Nature Structural Biology 1, 146-147
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Data based modelling of proteins (1994)
In: Statistical Mechanics, Protein Structure and Protein Substrate Interactions
Plenum Press, New York
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LexA repressor and iron uptake regulator from Escherichia coli: new members of the CAP-like DNA binding domain superfamily (1994)
Protein Engineering 7,1449-1453
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Reconstruction of symmetry related molecules from Protein Data Bank (PDB) files (1994)
J. Appl. Cryst. 27, 1006-1009
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A novel RNA_binding motif in omnipotent suppressors of translation termination, ribosomal proteins and a ribosome modification enzyme (1994)
Nucl. Ac. Res. 22: 2166-2167
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A common step for signal transduction in G protein coupled receptors (1994)
TIPS 15, 170-172
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1D secondary structure prediction through evolutionary profiles (1994)
In: Protein Structure by Distance Analysis
Amsterdam: IOS Press
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Evolution and neural networks - Protein secondary structure prediction above 71% accuracy (1994)
In: 27th Hawaii International Conference on System Sciences, Wailea, Hawaii, vol. 5
IEEE Society Press
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Can three-dimensional contacts in protein structures be predicted by analysis of correlated mutations? (1994)
Protein Engineering 7, 349-358
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The HSSP database of protein sequence-structure alignments (1994)
Nucleic Acids Research 22, 3597-3599
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A hybrid protein kinase - RNAase in an interferon-induced pathway (1994)
FEBS Letters 334, 149-152
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The FSSP database of structurally aligned protein fold families (1994)
Nucleic Acids Research 21, 3105-3109
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Design of protein structures: helical bundles and beyond (1994)
Trends in Biotechnology 12, 163-167
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A novel search method for protein sequence-structure relationships using property profiles (1994)
Protein Engineering 7, no. 1
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The intracellular localization of bacterial division protein FtsA, a member of the actin family, correlates with its phosphorylation state and its ATP-binding capacity (1994)
EMBO J. 13, 4919-4925
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The immunoglobulin fold: structural classification, sequence patterns, and common core (1994)
J. Mol. Biol. 242, 309-320
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GeneQuiz: a workbench for sequence analysis (1994)
In: Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology
AAAI Press, Menlo Park, CA
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Conservation and prediction of solvent accessibility in protein families (1994)
Proteins, 20, 216-226
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Redefining the goals of secondary structure prediction (1994)
J. Mol. Biol. 235, 13-26
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Structure prediction of proteins - where are we now? (1994)
Curr. Opin. Biotech. 5, 372-380
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Combining evolutionary information and neural networks to predict protein secondary structure (1994)
Proteins19, 55-72
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PHD- an automatic mail server for protein secondary structure prediction (1994)
CABIOS 10, 53-60
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Molecular modelling using WHATIF on personal computers (1994)
Chemical Design Automation News, May 1994, 11-13.
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Prediction of protein structure by evaluation of sequence-structure fitness: aligning sequences to contact profiles derived from 3D structures (1993)
J. Mol. Biol. 232, 805-825
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The HSSP data base of protein sequence-structure alignments (1993)
Nucleic Acids Research 21, 3105-3109
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Convergent evolution of similar enzymatic function on different protein folds: the hexokinase, ribokinase and galactokinase families of sugar kinases (1993)
Protein Science 2, 31-40
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Protein structure comparison by alignment of distance matrices (1993)
J. Mol. Biol. 233, 123-138
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Structural alignment of globins, phycocyanins and colicin A (1993)
Febs Letters 315, 301-306
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A new ATP binding fold. A common structure for actin, hexokinase and the Nt domain of Hsc70 (1993)
Trends in Cell Biology 3, 53-59
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Prokaryotic members of a new family of putative helicases with similarity to the transcription activator SNF2 (1993)
J. Mol. Biol. 230, 684-688
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Norrie disease protein (NDP) is a cysteine knot growth factor (1993)
Nature Genetics 5, 376-380
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Homology of the NifS family of proteins to a new class of pyridoxal phosphate-dependent enzymes (1993)
FEBS Letters 322, 159-164
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Prokaryotic polyphosphate phosphatases belong to the actin/hsp70/sugar kinase superfamily (1993)
TIBS 18, 247-248
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Improved prediction of protein secondary structure by use of sequence profiles and neural networks (1993)
P.N.A.S. USA 90, 7558-7562
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Prediction of protein secondary structure at better than 70% accuracy (1993)
J.Mol.Biol. 232, 584-599
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Secondary structure prediction of all-helical proteins in two states (1993)
Protein Engineering 8, 831-836
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From Sequence Similarity to Structural Homology of Proteins in: Computation of Biomolecular Structures (1993)
In: Achievements, Problems and Perspectives
Springer Verlag
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An efficient solvation term for use in protein simulations based on atomic occupancies (1993)
Molecular Simulation 10, 97-120
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Quality Control of Protein Models: Directional Atomic Contact Analysis (1993)
J. Appl. Cryst. 26, 47-60
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A new triple-helical model for the shaft of the adenovirus fibre (1992)
J. Mol. Graphics 10, 12-16
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The human genome and high performance computing in molecular biology (1992)
In: Supercomputer 1992
Springer-Verlag, Berlin
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A large domain common to sperm receptors (Zp2 and Zp3) and TGF-b type III receptor (1992)
FEBS Letters 300, 237-240
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Comprehensive sequence analysis of the 182 predicted open reading frames of yeast chromosome III (1992)
Protein Science 1, 1677-1690
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A module of the DnaJ heat shock proteins found in malaria parasites (1992)
TIBS 17, 129-129
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The internalization signal in the cytoplasmic tail of lysosomal acid phosphatase consists of the hexapeptide PGYRHV (1992)
EMBO J. 11, 4391-4399
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An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins (1992)
PNAS USA 89, 7290-7294
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Fast and simple Monte Carlo algorithm for sidechain optimization in proteins. Application to model building by homology (1992)
Proteins 14, 213-223
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Evaluation of protein models by atomic solvation preference (1992)
J. Mol. Biol. 225, 93-105
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A database of protein structure families with common folding motifs (1992)
Protein Science 1, 1691-1698
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TFIIB, an evolutionary link between the transcription machineries of archaebacteria and eukaryotes (1992)
Cell 71, 189-190
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Molecular Cloning and Structural Analysis of Genes from Zea mays (L.) coding for members of the ras-related YPT gene family (1992)
P.N.A.S. USA 89, 787-791
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Design of Protein Structures (1992)
In Protein Engineering, a Practical Approach, A.R.Rees, M.J.E. Sternberg and R. Wetzel eds., Oxford University Press, 1992, p 89- 115 (not refereed)
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Exercising Multi-layered Networks on Protein Secondary Structure.International (1992)
Journal of Neural Systems 3 (Supp. 1992), 209-220
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A new triple-helical model for the shaft of the adenovirus fibre (1992)
J. Mol. Biol. 226, 1073-1084
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Protein Design on Computers. Five new proteins: Shpilka, Grendel, Fingerclasp, Leather and Aida (1992)
Proteins 12, 105-110
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The essential tyrosine of the internalization signal of lysosomal acid phosphatase is part of a beta-turn (1991)
Cell 67, 1203-1209
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Identification by computer sequence analysis of transcriptional regulator proteins in dictyostelium discoideum and serratia marcescens (1991)
Nucl. Acids Res. 19, 2359-2362
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Database algorithm for generating protein backbone and side chain coordinates from a C(alpha) trace. Application to model building and detection of coordinate errors (1991)
J. Mol. Biol. 218, 183-194
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The functional mechanism of heat shock and chaperone proteins in protein folding. A hypothesis (1991)
Protein Engineering 4, 711-717
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A structure-derived sequence pattern for the type I copper binding domain in distantly related proteins (1991)
FEBS Letters 279, 73-78
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(HX)n repeats: a pH-controlled protein-protein interaction motif of eukaryotic transcription factors? (1991)
FEBS Letters 295, 1-2
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Database of homology-derived protein structures and the structural meaning of sequence alignment (1991)
Proteins 9, 56-68
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The ras Protein Family: Evolutionary Tree and Role of Conserved Amino Acids (Perspectives in Biochemistry) (1991)
Biochemistry 30, 4637-4648
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G-domains of ras p21 oncogene protein and elongation factor Tu: analysis of three-dimensional structures, sequence families and functional sites (1991)
PNAS 88, 5443-5447
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Detection of common three-dimensional substructures in proteins (1991)
Proteins 11, 52-58
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Molecular cloning of YPT1/SEC4-related cDNAs from an epithelial line (1990)
Mol. Cell. Biol. 10, 6578-6585
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Excluded Volume Approximation to Protein-Solvent Interaction: the Solvent Contact Model (1990)
Biophysical Journal 57, 1103-1107
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Proton NMR assignments and secondary structure determination of the ColE1 rop (rom) protein (1990)
Biochemistry 29, 7402-7407
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Identification of guanine-nucleotide binding proteins in plants: structural and evolutionary analysis of the ras-related YPT gene family from Zea Mays (1989)
In: The guanine-nucleotide Binding Proteins Common Structural and Functional Properties
Plenum, New York
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How to determine protein secondary structure in solution by Raman spectroscopy: Practical guide and test case DNAse I (1989)
Biochemistry 28, 4271-4277
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Polarity as a criterion in protein design (1989)
Protein Engineering 2 (1989) 329-334
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Thermitase, a Thermostable Subtilisin: Comparison of Predicted and Experimental Structures and the Molecular Cause of Thermostability (1989)
Proteins 5, 22-37
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Residue contact conservation in a family of Ca-binding proteins (1989)
Protein Engineering 2 (1989) 589-596
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Cassette mutagenesis to produce designed ROP protein variants (1988)
In: Advances in Protein Design, GBF Workshop, Braunschweig
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Immunization with synthetic peptides of plasmodium falciparum surface antigen induces antimerozoite antibodies (1986)
Proc. Natl. Acad. Sci. (USA) 83, 8328-8332
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The primary structure of transcription factor TFIIIA has twelve consecutive repeats (1985)
FEBS Letters 186, 271-273
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Protein normal-mode dynamics: trypsin inhibitor, crambin, ribonuclease and lysozyme (1985)
J. Mol. Biol. 181, 423-447
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On the use of sequence homologies to predict protein structure: identical pentapeptides can have completely different conformations (1984)
Proc. Natl. Acad. Sci. (USA) 81, 1075-1078
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A yeast gene encoding a protein homologous to the human c-Ha-ras proto-oncogene product (1983)
Nature 306, 704-707 (paper) and 306, 642-642 (news and views)
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Toward peptide vaccines: prediction of antigenic peptides from protein sequences of influenza virus and foot and mouth disease virus. (Meeting Abstract, material not published elsewhere) (1983)
Hoppe-Seyler's Zeitschrift fuer Physiol. Chemie 364, 1152
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How good are predictions of protein secondary structure? (1983)
FEBS Letters 155, 179-182
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Dictionary of protein secondary structure. Pattern recognition of hydrogen bonded and geometrical features (1983)
Biopolymers 22, 2577-2637
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Collective Protein Dynamics: a Film of the Low Frequency Normal Modes of Trypsin Inhibitor (1983)
Hoppe-Seyler's Zeitschrift f?r Physiol. Chemie 364, 1262
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The normal modes of a protein: native bovine pancreatic trypsin inhibitor (1983)
Internatl. J. Quant. Chem., Quantum Biology Symposium 10, 181-199
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Physical criteria for folding units of globular proteins (1981)
In: Structural Aspects of Recognition and Assembly in Biological Macromolecules
nternational Science Services, Rehovot and Philadelphia
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Dipoles of the alpha-helix and the beta-sheet: their role in protein folding (1981)
Nature 294, 532-536. and 295, 13-15. (news and views)
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Specific recognition in the tertiary structure of beta-sheets of proteins (1980)
J. Mol. Biol. 139, 627-639
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Degeneracy of the information contained in amino acid sequences: evidence from overlaid genes (1979)
J. Mol. Evol. 13, 245-252
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Antiparallel and parallel beta-strands differ in amino acid residue preferences (1979)
Nature 282, 109-111
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A multitude of genes expressed solely in meiotic or postmeiotic spermatogenic cells offers a myriad of contraceptive targets (2003)
Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12201-6. Epub 2003 Oct 02
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A mammalian microRNA expression atlas based on small RNA library sequencing. (2007)
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A novel class of small RNAs bind to MILI protein in mouse testes. (2006)
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(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway. (2009)
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Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis. (2009)
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The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers. (2009)
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An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors. (2009)
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Genetic predictors of MEK dependence in non-small cell lung cancer. (2008)
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Comprehensive genomic characterization defines human glioblastoma genes and core pathways. (2008)
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Humoral response profiling reveals pathways to prostate cancer progression. (2007)
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Differential proteomic alterations between localised and metastatic prostate cancer. (2006)
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A systems approach to model metastatic progression. (2006)
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