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Publications
Variability and robustness in T cell activation from regulated heterogeneity in protein levels. (2008)
Science. 2008 Aug 22;321(5892):1081-4.
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Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs. (2009)
Nat Biotechnol. 2009 Jun;27(6):549-55.
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Characterization of small RNAs in aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB. (2009)
Neuron. 2009 Sep 24;63(6):803-17.
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The microRNA.org resource: targets and expression. (2008)
Nucleic Acids Res. 2008 Jan;36(Database issue):D149-53.
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Eradication of chronic myeloid leukemia stem cells: a novel mathematical model predicts no therapeutic benefit of adding G-CSF to imatinib. (2009)
PLoS Comput Biol. 2009 Sep;5(9):e1000503.
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Evolution of Resistance to Targeted Anti-Cancer Therapies during Continuous and Pulsed Administration Strategies. (2009)
PLoS Comput Biol. 2009 Nov;5(11):e1000557.
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A progenitor cell origin of myeloid malignancies. (2009)
Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16616-21.
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RANKPROP: a web server for protein remote homology detection. (2009)
Bioinformatics. 2009 Jan 1;25(1):121-2.
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Identification of DNA-binding proteins using structural, electrostatic and evolutionary features. (2009)
J Mol Biol. 2009 Apr 10;387(4):1040-53.
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Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs. (2009)
Nat Biotechnol. 2009 Jun;27(6):549-55.
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Combining classifiers for improved classification of proteins from sequence or structure. (2008)
BMC Bioinformatics. 2008;9:389.
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A predictive model of the oxygen and heme regulatory network in yeast. (2008)
PLoS Comput Biol. 2008 Nov;4(11):e1000224.
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Eradication of chronic myeloid leukemia stem cells: a novel mathematical model predicts no therapeutic benefit of adding G-CSF to imatinib. (2009)
PLoS Comput Biol. 2009 Sep;5(9):e1000503.
[ Back to Top ]
Evolution of Resistance to Targeted Anti-Cancer Therapies during Continuous and Pulsed Administration Strategies. (2009)
PLoS Comput Biol. 2009 Nov;5(11):e1000557.
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A progenitor cell origin of myeloid malignancies. (2009)
Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16616-21.
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Mathematical models of cancer stem cells. (2008)
J Clin Oncol. 2008 Jun 10;26(17):2854-61.
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A one-mutation mathematical model can explain the age incidence of acute myeloid leukemia with mutated nucleophosmin (NPM1). (2008)
Haematologica. 2008 Jul 4;
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(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway. (2009)
Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4519-24.
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Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis. (2009)
Nat Genet. 2009 May;41(5):524-6.
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The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers. (2009)
Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9435-40.
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An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors. (2009)
Oncogene. 2009 Jun 15;
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Genetic predictors of MEK dependence in non-small cell lung cancer. (2008)
Cancer Res. 2008 Nov 15;68(22):9375-83.
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Comprehensive genomic characterization defines human glioblastoma genes and core pathways. (2008)
Nature. 2008 Oct 23;455(7216):1061-8.
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Ab initio thermodynamic modeling of distal multisite transcription regulation. (2008)
Nucleic Acids Res. 2008 Feb;36(3):726-31.
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Failure of the work-Hamiltonian connection for free-energy calculations. (2008)
Phys Rev Lett. 2008 Jan 18;100(2):020601.
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The microRNA.org resource: targets and expression. (2008)
Nucleic Acids Res. 2008 Jan;36(Database issue):D149-53.
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Statistics is Easy! (2008)
Synthesis Lectures on Mathematics and Statistics Jan 2008, Vol. 1, No. 1: 1-82.
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