Computational Biology Center Publications

Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses (2012)

Rachel A Gottschalk, Matthew M Hathorn, Hlne Beuneu, Emily Corse, Michael L Dustin, Grgoire Altan-Bonnet, James P Allison

PNAS

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A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells (2011)

Emily J Quann, Xin Liu, Grgoire Altan-Bonnet, Morgan Huse

Nature Immunology

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Ethan Cerami

Integrated genomic analyses of ovarian carcinoma (2011)

The Cancer Genome Atlas Research Network

Nature. 2011 Jun 29;474(7353):609-15.

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Christina Leslie

Genomic safe harbors permit high &946;-globin transgene expression in thalassemia induced pluripotent stem cells. (2011)

Papapetrou EP, Lee G, Malani N, Setty M, Riviere I, Tirunagari LM, Kadota K, Roth SL, Giardina P, Viale A, Leslie C, Bushman FD, Studer L, Sadelain M.

Nat Biotechnol. 2011 Jan;29(1):73-8. Epub 2010 Dec 12

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Detecting remote evolutionary relationships among proteins by large-scale semantic embedding. (2011)

Melvin I, Weston J, Noble WS, Leslie C

PLoS Comput Biol. 2011 Jan 27;7(1):e1001047.

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Computational and experimental identification of mirtrons in Drosophila melanogaster and Caenorhabditis elegans. (2011)

Chung WJ, Agius P, Westholm JO, Chen M, Okamura K, Robine N, Leslie CS, Lai EC.

Genome Res. 2011 Feb;21(2):286-300. Epub 2010 Dec 22.

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A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL) (2011)

Mavrakis KJ, Van Der Meulen J, Wolfe AL, Liu X, Mets E, Taghon T, Khan AA, Setti M, Rondou P, Vandenberghe P, Delabesse E, Benoit Y, Socci NB, Leslie CS, Van Vlierberghe P, Speleman F, Wendel HG.

Nat Genet. 2011 Jul 27;43(8):815. doi: 10.1038/ng0811-815b.

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Chris Sander

Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-beta pathway and reveal microRNA regulation of TGFBR2. (2011)

Schultz N, Marenstein DR, De Angelis DA, Wang WQ, Nelander S, Jacobsen A, Marks DS, Massague J, Sander C

Silence. 2011;2:3.

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18F-fluorodeoxy-glucose positron emission tomography (18FDG-PET) marks MYC-overexpressing human basal-like breast cancers. (2011)

Palaskas NJ, Larson SM, Schultz N, Komisopoulou E, Wong J, Rohle D, Campos C, Yannuzzi N, Osborne JR, Linkov I, Kastenhuber E, Taschereau R, Plaisier SB, Tran C, Heguy A, Wu H, Sander C, Phelps ME, Brennan CW, Port E, Huse JT, Graeber TG, Mellinghoff I.

Cancer Res. 2011 Aug 1;71(15):5164-5174.

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Identification of PHLPP1 as a Tumor Suppressor Reveals the Role of Feedback Activation in PTEN-Mutant Prostate Cancer Progression. (2011)

Chen M, Pratt CP, Zeeman ME, Schultz N, Taylor BS, ONeill A, Castillo-Martin M, Nowak DG, Naguib A, Grace DM, Murn J, Navin N, Atwal GS, Sander C, Gerald WL, Cordon-Cardo C, Newton AC, Carver BS, Trotman LC.

Cancer Cell. 2011 Aug 16;20(2):173-86.

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Integrated genomic analyses of ovarian carcinoma (2011)

The Cancer Genome Atlas Research Network

Nature. 2011 Jun 29;474(7353):609-15.

[PubMed Abstract] [Full Text] [PDF]

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