Publications
Altan-Bonnet Group Robustness and adaptability of self/non-self discrimination in the immune system Chodera Group Computational design of small molecules for drug discovery; functional dynamics of kinases; multiscale simulation of cellular pathways; statistical mechanics; computational chemistry Leslie Group Cell-type specific transcriptional programs; co- and post-transcriptional regulation; cancer systems biology Rätsch Group Machine learning, computational transcriptomics, computational genome annotation, sequence variation Sander Group Computational and systems biology; design of combinatorial cancer therapy; cancer genomics and proteomics; molecular pathways and networks; 3D protein structure prediction Xavier Group Evolutionary conflict and cooperation in microbial pathogens; species interaction dynamics in the gut microbiome; cell-cell communication in cancer Bioinformatics Core Bioinformatics consultation, training, and resource development
CCSB at MSKCC
The Center for Cancer Systems Biology (CCSB) at MSKCC is investigating tumor cell heterogeneity, both within tumors and among patients, to gain insight needed for the development of subtype-specific and patient-specific cancer therapies. more
MSKCC Center for Translational Cancer Genomic Analysis
The MSKCC Center for Translational Cancer Genomic Analysis aims to develop novel integrative analysis methods for studying cancer genomic data, thereby enabling the translation of genomic insights into new clinical applications. more