David Kuo

David Kuo
Rätsch Research Group
Room: Z-695
Tel: +1 646 888 3394
Mailing Address: MSKCC – Computational Biology Center
1275 York Avenue, Box # 357
New York, NY 10065
Express Mail/Street Address: Zuckerman Research Center
417 East 68th Street – 6th Floor (Z-677)
New York, NY 10065

David Kuo applies machine learning methods to biomedical questions, specifically in the realm of cancer transcriptomics and large scale data analysis.

David began biomedical research in the laboratory of alternative splicing expert Jane Wu in the summers from 2001-2005. He earned his BS in Biological Sciences at Stanford University in 2008. While at Stanford, David was an undergraduate student researcher in the laboratory of cancer biologist Calvin Kuo (no relation), where he studied the effects of VEGF blockade on liver vasculature. David was an Information Systems Developer for McMaster-Carr Supply Company before matriculating at the Weill Cornell Graduate School of Medical Sciences in the Physiology, Biophysics & Systems Biology Department. He joined the Rätsch Lab in 2012.

Selected Publications:


  1. Wei K, Piecewicz SM, McGinnis LM, Taniguchi CM, Wiegand SJ, Anderson K, Chan CW, Mulligan KX, Kuo D, Yuan J, Vallon M, Morton LC, Lefai E, Simon MC, Maher JJ, Mithieux G, Rajas F, Annes JP, McGuinness OP, Thurston G, Giaccia AJ, Kuo CJ. A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition. Nature Medicine. 19(10):1331-1337, 2013. Pubmed
  2. Mordes D, Luo X, Kar A, Kuo D, Xu L, Fushimi K, Yu G, Sternberg P, Wu JY. Pre-mRNA splicing and retinitis pigmentosa. Molecular Vision. 12:1259-71., 2006. Pubmed
  3. Wu JY, Kar A, Kuo D, Yu B, Havlioglu N. SRp54 (SFRS11), a regulator for tau exon 10 alternative splicing identified by an expression cloning strategy. Molecular and Cellular Biology. 26(18):6739-47, 2006. Pubmed
  4. Kar A, Kuo D, He R, Zhou J, Wu JY. Tau alternative splicing and frontotemporal dementia. Alzheimer Disease & Associated Disorders. 19 Suppl 1:S29-46, 2005. Pubmed